Feasibility of Immunosuppressant Drug Monitoring by a Microsampling Device | Zendy

Valentinas Gruzdys | Zendy; Stephen D. Merrigan | Zendy; Kamisha L. JohnsonDavis | Zendy

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Feasibility of Immunosuppressant Drug Monitoring by a Microsampling Device

Author(s) -

Valentinas Gruzdys,

Stephen D. Merrigan,

Kamisha L. JohnsonDavis

Publication year - 2019

Publication title -

the journal of applied laboratory medicine

Language(s) - English

Resource type - Journals

eISSN - 2576-9456

pISSN - 2475-7241

DOI - 10.1373/jalm.2018.028126

Subject(s) - everolimus , sirolimus , tacrolimus , therapeutic drug monitoring , whole blood , analyte , medicine , transplantation , pharmacology , immunosuppressive drug , venous blood , urology , pharmacokinetics , chemistry , chromatography , surgery

Therapeutic drug monitoring (TDM) for immunosuppressive (ISP) drugs is an important component of organ and tissue transplantation and chemotherapy management. Whole blood is the specimen type for the quantitative analysis of cyclosporine A, everolimus, sirolimus, and tacrolimus. Some alternatives to venous whole blood samples have the potential to reduce blood volume requirements and simplify sample collection and transport.

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