Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion | Zendy

Jose CoelhoLima | Zendy; Ashfaq Mohammed | Zendy; Suzanne Cormack | Zendy; Samuel Jones | Zendy; Adnan Ali | Zendy; Pedram Panahi | Zendy; Matt J. Barter | Zendy; Alan Bagnall | Zendy; Simi Ali | Zendy; David A. Young | Zendy; Ioakim Spyridopoulos | Zendy

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Kinetics Analysis of Circulating MicroRNAs Unveils Markers of Failed Myocardial Reperfusion

Author(s) -

Jose CoelhoLima,

Ashfaq Mohammed,

Suzanne Cormack,

Samuel Jones,

Adnan Ali,

Pedram Panahi,

Matt J. Barter,

Alan Bagnall,

Simi Ali,

David A. Young,

Ioakim Spyridopoulos

Publication year - 2019

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2019.308353

Subject(s) - medicine , percutaneous coronary intervention , myocardial infarction , cardiology , microrna , cohort , biology , gene , biochemistry

Failed myocardial reperfusion occurs in approximately 50% of patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI). It manifests as microvascular obstruction (MVO) on cardiac magnetic resonance (CMR) imaging. Although prognostically important, MVO is not routinely screened for. Our aim was to investigate the kinetics of circulating short noncoding ribonucleic acids [microRNAs (miRNAs)] following PPCI and their association with MVO in STEMI patients.

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