Gene Expression Signatures in Circulating Tumor Cells Correlate with Response to Therapy in Metastatic Breast Cancer
Author(s) -
Maren Bredemeier,
Philippos Edimiris,
Paweł Mach,
Mikael Kubista,
Robert Sjöback,
Eva Rohlova,
Katarína Kološtová,
Siegfried Hauch,
Bahriye Aktas,
Mitra Tewes,
Rainer Kimmig,
Sabine KasimirBauer
Publication year - 2017
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2016.269605
Subject(s) - circulating tumor cell , metastatic breast cancer , cdh1 , medicine , breast cancer , muc1 , cancer research , cancer , oncology , metastasis , biology , cell , cadherin , genetics
Circulating tumor cells (CTCs) are thought to be an ideal surrogate marker to monitor disease progression in metastatic breast cancer (MBC). We investigated the prediction of treatment response in CTCs of MBC patients on the basis of the expression of 46 genes.
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