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Direct Comparison of 2 Rule-Out Strategies for Acute Myocardial Infarction: 2-h Accelerated Diagnostic Protocol vs 2-h Algorithm
Author(s) -
Karin Wildi,
Louise Cullen,
Raphael Twerenbold,
Jaimi Greenslade,
William Parsonage,
Jasper Boeddinghaus,
Thomas Nestelberger,
Zaid Sabti,
María Rubini Giménez,
Christian Puelacher,
Janosch Cupa,
Lukas Schumacher,
Patrick Badertscher,
Karin Grimm,
Nikola Kozhuharov,
Claudia Stelzig,
Michael Freese,
Katharina Rentsch,
Jens Lohrmann,
Wanda Kloos,
Andreas Buser,
Tobias Reichlin,
John W. Pickering,
Martin Than,
Christian Mueller
Publication year - 2017
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2016.268359
Subject(s) - medicine , myocardial infarction , chest pain , acute coronary syndrome , cardiology , troponin , emergency department , triage , algorithm , biomarker , diagnostic accuracy , troponin i , predictive value of tests , emergency medicine , biochemistry , chemistry , psychiatry , computer science
We compared 2 high-sensitivity cardiac troponin (hs-cTn)-based 2-h strategies in patients presenting with suspected acute myocardial infarction (AMI) to the emergency department (ED): the 2-h accelerated diagnostic protocol (2h-ADP) combining hs-cTn, electrocardiogram, and a risk score, and the 2-h algorithm exclusively based on hs-cTn concentrations and their absolute changes.

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