Paper-Based MicroRNA Expression Profiling from Plasma and Circulating Tumor Cells | Zendy

Sai Mun Leong | Zendy; Karen Tan | Zendy; Hui Wen Chua | Zendy; Mo-Chao Huang | Zendy; Wai Chye Cheong | Zendy; MoHuang Li | Zendy; Steven Tucker | Zendy; Evelyn Siew-Chuan Koay | Zendy

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Paper-Based MicroRNA Expression Profiling from Plasma and Circulating Tumor Cells

Author(s) -

Sai Mun Leong,

Karen Tan,

Hui Wen Chua,

Mo-Chao Huang,

Wai Chye Cheong,

MoHuang Li,

Steven Tucker,

Evelyn Siew-Chuan Koay

Publication year - 2017

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2016.264432

Subject(s) - microrna , circulating tumor cell , digital polymerase chain reaction , whole blood , computational biology , cancer research , cancer , biology , metastasis , medicine , immunology , polymerase chain reaction , gene , biochemistry

Molecular characterization of circulating tumor cells (CTCs) holds great promise for monitoring metastatic progression and characterizing metastatic disease. However, leukocyte and red blood cell contamination of routinely isolated CTCs makes CTC-specific molecular characterization extremely challenging.

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