Biomarkers and Genetics in Peripheral Artery Disease | Zendy

Surovi Hazarika | Zendy; Brian H. Annex | Zendy

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Biomarkers and Genetics in Peripheral Artery Disease

Author(s) -

Surovi Hazarika,

Brian H. Annex

Publication year - 2016

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2016.263798

Subject(s) - disease , medicine , human genetics , biomarker , identification (biology) , arterial disease , bioinformatics , intensive care medicine , pathology , vascular disease , biology , gene , genetics , botany

Peripheral artery disease (PAD) is highly prevalent and there is considerable diversity in the initial clinical manifestation and disease progression among individuals. Currently, there is no ideal biomarker to screen for PAD, to risk stratify patients with PAD, or to monitor therapeutic response to revascularization procedures. Advances in human genetics have markedly enhanced the ability to develop novel diagnostic and therapeutic approaches across a host of human diseases, but such developments in the field of PAD are lagging.

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