Glial Fibrillary Acidic Protein Serum Levels Distinguish between Intracerebral Hemorrhage and Cerebral Ischemia in the Early Phase of Stroke | Zendy

Sebastian Luger | Zendy; Jens Witsch | Zendy; Andreas Dietz | Zendy; Gerhard F. Hamann | Zendy; Jens Minnerup | Zendy; Hauke Schneider | Zendy; Matthias Sitzer | Zendy; Katja E. Wartenberg | Zendy; Marion Niessner | Zendy; Christian Foerch | Zendy

Open Access

Glial Fibrillary Acidic Protein Serum Levels Distinguish between Intracerebral Hemorrhage and Cerebral Ischemia in the Early Phase of Stroke

Author(s) -

Sebastian Luger,

Jens Witsch,

Andreas Dietz,

Gerhard F. Hamann,

Jens Minnerup,

Hauke Schneider,

Matthias Sitzer,

Katja E. Wartenberg,

Marion Niessner,

Christian Foerch

Publication year - 2016

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2016.263335

Subject(s) - glial fibrillary acidic protein , intracerebral hemorrhage , ischemia , stroke (engine) , medicine , brain ischemia , ischemic stroke , phase (matter) , pathology , chemistry , subarachnoid hemorrhage , immunohistochemistry , engineering , organic chemistry , mechanical engineering

Recent studies have suggested that glial fibrillary acidic protein (GFAP) serum concentrations distinguish between intracerebral hemorrhage (ICH) and ischemic stroke (IS) shortly after symptom onset. In this prospective multicenter trial we validated GFAP in an independent patient cohort and assessed the quantitative relationship between GFAP release, bleeding size, and localization.

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