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Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells
Author(s) -
Tobias M. Gorges,
Andra Kuske,
Katharina Röck,
Oliver Mauermann,
Volkmar Müller,
Sven Peine,
Karl Verpoort,
Vendula Novosadová,
Mikael Kubista,
Sabine Riethdorf,
Klaus Pantel
Publication year - 2016
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2016.260299
Subject(s) - biology , circulating tumor cell , cancer research , transcriptome , tumor microenvironment , tumor progression , gene expression profiling , cd44 , cancer , gene expression , metastasis , cell , gene , genetics , tumor cells
Transcriptome analysis of circulating tumor cells (CTCs) holds great promise to unravel the biology of cancer cell dissemination and identify expressed genes and signaling pathways relevant to therapeutic interventions.

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