Open AccessWaste, Leaks, and Failures in the Biomarker Pipeline
Author(s) -
John P. A. Ioannidis,
Patrick M. Bossuyt
Publication year - 2017
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2016.254649
Subject(s) - biomarker , biomarker discovery , risk analysis (engineering) , clinical trial , pipeline (software) , computer science , medicine , intensive care medicine , data science , pathology , biology , proteomics , biochemistry , gene , programming language
The large, expanding literature on biomarkers is characterized by almost ubiquitous significant results, with claims about the potential importance, but few of these discovered biomarkers are used in routine clinical care.
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