Pediatric Population Reference Value Distributions for Cancer Biomarkers and Covariate-Stratified Reference Intervals in the CALIPER Cohort | Zendy

Victoria Bevilacqua | Zendy; Man Khun Chan | Zendy; Yunqi Chen | Zendy; David Armbruster | Zendy; Beth A. Schodin | Zendy; Khosrow Adeli | Zendy

Open Access

Pediatric Population Reference Value Distributions for Cancer Biomarkers and Covariate-Stratified Reference Intervals in the CALIPER Cohort

Author(s) -

Victoria Bevilacqua,

Man Khun Chan,

Yunqi Chen,

David Armbruster,

Beth A. Schodin,

Khosrow Adeli

Publication year - 2014

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2014.229799

Subject(s) - calipers , covariate , medicine , cohort , statistics , reference values , population , cohort study , oncology , mathematics , environmental health , geometry

Cancer biomarkers are commonly used in pediatrics to monitor cancer progression, recurrence, and prognosis, but pediatric reference value distributions have not been well established for these markers. The Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) sought to develop a pediatric database of covariate-stratified reference value distributions for 11 key circulating tumor markers, including those used in assessment of patients with childhood or adult cancers.

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