Gene Expression Profiling of Circulating Tumor Cells in Breast Cancer | Zendy

Emanuela Fina | Zendy; Maurizio Callari | Zendy; Carolina Reduzzi | Zendy; Francesca D’Aiuto | Zendy; Gabriella Mariani | Zendy; Daniele Generali | Zendy; Marco A. Pierotti | Zendy; Maria Grazia Daidone | Zendy; Vera Cappelletti | Zendy

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Gene Expression Profiling of Circulating Tumor Cells in Breast Cancer

Author(s) -

Emanuela Fina,

Maurizio Callari,

Carolina Reduzzi,

Francesca D’Aiuto,

Gabriella Mariani,

Daniele Generali,

Marco A. Pierotti,

Maria Grazia Daidone,

Vera Cappelletti

Publication year - 2014

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2014.229476

Subject(s) - circulating tumor cell , epithelial cell adhesion molecule , biology , breast cancer , gene expression , breast carcinoma , cancer , cancer research , antibody , microbiology and biotechnology , gene , immunology , metastasis , genetics

Determining the transcriptional profile of circulating tumor cells (CTCs) may allow the acquisition of clinically relevant information while overcoming tumor heterogeneity-related biases associated with use of tissue samples for biomarker assessment. However, such molecular characterization is challenging because CTCs are rare and outnumbered by blood cells.

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