Microfluidic Genotyping by Rapid Serial PCR and High-Speed Melting Analysis
Author(s) -
Scott O. Sundberg,
Carl T. Wittwer,
Renee Howell,
Jarkko Huuskonen,
Robert J. Pryor,
Jared S. Farrar,
Heather M Stiles,
Robert Palais,
Ivor Knight
Publication year - 2014
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2014.223768
Subject(s) - genotyping , polymerase chain reaction , microfluidics , chromatography , computational biology , biology , genetics , chemistry , genotype , materials science , nanotechnology , gene
Clinical molecular testing typically batches samples to minimize costs or uses multiplex lab-on-a-chip disposables to analyze a few targets. In genetics, multiple variants need to be analyzed, and different work flows that rapidly analyze multiple loci in a few targets are attractive.
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