Open AccessConsiderations for Digital PCR as an Accurate Molecular Diagnostic Tool
Author(s) -
Jim F. Huggett,
Simon Cowen,
Carole A. Foy
Publication year - 2014
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2014.221366
Subject(s) - digital polymerase chain reaction , computer science , computational biology , medical physics , medicine , biology , polymerase chain reaction , genetics , gene
Digital PCR (dPCR) is an increasingly popular manifestation of PCR that offers a number of unique advantages when applied to preclinical research, particularly when used to detect rare mutations and in the precise quantification of nucleic acids. As is common with many new research methods, the application of dPCR to potential clinical scenarios is also being increasingly described.
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