Open AccessHuman miRNome Profiling Identifies MicroRNAs Differentially Present in the Urine after Kidney Injury
Author(s) -
Krithika Ramachandran,
Janani Saikumar,
Vanesa Bijol,
Jay L. Koyner,
Jing Qian,
Rebecca A. Betensky,
Sushrut S. Waikar,
Vishal S. Vaidya
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2013.210245
Subject(s) - acute kidney injury , urine , microrna , medicine , cohort , intensive care unit , biomarker , kidney , urology , gene , biology , genetics
Extracellular microRNAs (miRNAs) have been proposed as potentially robust and stable biomarkers of various disease conditions. The primary objective of this study was to identify miRNAs differentially occurring in the urine that could serve as potential biomarkers of acute kidney injury (AKI), because traditional AKI markers have limitations with respect to sensitivity, specificity, and timeliness of diagnosis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom