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The Importance of Commutability of Reference Materials Used as Calibrators: The Example of Ceruloplasmin
Author(s) -
Ingrid Zegers,
Robert Beetham,
Thomas Keller,
Julie Sheldon,
David Bullock,
Finlay MacKenzie,
Stefanie Trapmann,
Hendrik Emons,
Heinz Schimmel
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.201954
Subject(s) - external quality assessment , ceruloplasmin , certified reference materials , medicine , reference values , mathematics , statistics , pathology , detection limit
Different methods for ceruloplasmin tend to give different results in external quality assessment schemes. During the production of the certified reference material ERM-DA470k/IFCC discrepant measurement results were also found for ceruloplasmin measured with different methods, and consequently the protein could not be certified in the material.

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