Change in Growth Differentiation Factor 15 Concentrations over Time Independently Predicts Mortality in Community-Dwelling Elderly Individuals
Author(s) -
Kai M. Eggers,
Tibor Kempf,
Lars Wallentin,
Kai C. Wollert,
Lars Lind
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.201210
Subject(s) - gdf15 , medicine , hazard ratio , renal function , natriuretic peptide , diabetes mellitus , proportional hazards model , prospective cohort study , endocrinology , heart failure , confidence interval
Growth differentiation factor 15 (GDF-15) is emerging as a powerful risk indicator in both cardiovascular disease patients and community-dwelling individuals. We investigated GDF-15 concentrations and their changes over 5 years in elderly individuals from the community, together with the underlying conditions and prognostic implications of these measurements.
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