Defining High-Sensitivity Cardiac Troponin Concentrations in the Community | Zendy

Paul M. McKie | Zendy; Denise M. Heublein | Zendy; Christopher G. Scott | Zendy; Mary Lou Gantzer | Zendy; Ramila A. Mehta | Zendy; Richard J. Rodeheffer | Zendy; Margaret M. Redfield | Zendy; John C. Burnett | Zendy; Allan S. Jaffe | Zendy

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Defining High-Sensitivity Cardiac Troponin Concentrations in the Community

Author(s) -

Paul M. McKie,

Denise M. Heublein,

Christopher G. Scott,

Mary Lou Gantzer,

Ramila A. Mehta,

Richard J. Rodeheffer,

Margaret M. Redfield,

John C. Burnett,

Allan S. Jaffe

Publication year - 2013

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2012.198614

Subject(s) - cohort , medicine , troponin i , cardiology , population , cohort study , renal function , troponin , body mass index , coronary artery disease , myocardial infarction , environmental health

High-sensitivity cardiac troponin (hs-cTn) assays are now available that can detect measurable troponin in significantly more individuals in the general population than conventional assays. The clinical use of these hs-cTn assays depends on the development of proper reference values. Therefore, our objective was to define hs-cTnI reference values and determinants in the general community, in a healthy reference cohort, and in subsets with diseases.

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