Epitope Specificity and IgG Subclass Distribution of Autoantibodies to Cardiac Troponin
Author(s) -
Tanja Savukoski,
Aleksandra TwardaClapa,
Sanna Hellberg,
Noora Ristiniemi,
Saara Wittfooth,
Juha Sinisalo,
Kim Pettersson
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.194860
Subject(s) - subclass , autoantibody , epitope , antibody , medicine , immunology
Autoantibodies to cardiac troponins (cTnAAbs) can interfere with the measurement of cardiac troponin I (cTnI) by immunoassays for the diagnosis of myocardial infarction. Therefore, we determined the cTnI binding sites and IgG subclasses of circulating cTnAAbs.
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