Antigen Microarrays for the Study of Autoimmune Diseases
Author(s) -
Ada Yeste,
Francisco J. Quintana
Publication year - 2013
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.194423
Subject(s) - antigen , immunology , immune system , autoimmune disease , dna microarray , microarray , protein microarray , medicine , disease , autoimmunity , biology , antibody , pathology , gene expression , gene , genetics
The immune response involves the activation of heterogeneous populations of T cells and B cells that show different degrees of affinity and specificity for target antigens. Although several techniques have been developed to study the molecular pathways that control immunity, there is a need for high-throughput assays to monitor the specificity of the immune response.
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