Vitamin D and Mortality: A Mendelian Randomization Study | Zendy

Olivia Trummer | Zendy; Stefan Pilz | Zendy; Michael M. Hoffmann | Zendy; Bernhard R. Winkelmann | Zendy; Bernhard O. Boehm | Zendy; Winfried März | Zendy; Thomas R. Pieber | Zendy; Barbara ObermayerPietsch | Zendy; Wilfried Renner | Zendy

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Vitamin D and Mortality: A Mendelian Randomization Study

Author(s) -

Olivia Trummer,

Stefan Pilz,

Michael M. Hoffmann,

Bernhard R. Winkelmann,

Bernhard O. Boehm,

Winfried März,

Thomas R. Pieber,

Barbara ObermayerPietsch,

Wilfried Renner

Publication year - 2013

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2012.193185

Subject(s) - mendelian randomization , vitamin d and neurology , randomization , vitamin , medicine , biology , genetics , clinical trial , gene , genetic variants , genotype

Decreased circulating 25-hydroxy-vitamin D (25-OH-vitamin D) concentrations have been associated with mortality rates, but it is unclear whether this association is causal. We performed a Mendelian randomization study and analyzed whether 3 common single-nucleotide polymorphisms (SNPs) associated with 25-OH-vitamin D concentrations are causal for mortality rates.

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