Evidence-Based Laboratory Medicine in Oncology Drug Development: From Biomarkers to Diagnostics
Author(s) -
Vijay Modur,
Eric Hailman,
J. Carl Barrett
Publication year - 2012
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.191072
Subject(s) - drug development , biomarker , companion diagnostic , medicine , precision medicine , biomarker discovery , cancer biomarkers , personalized medicine , drug , translational research , cancer , cancer medicine , medical physics , bioinformatics , oncology , pathology , pharmacology , proteomics , biology , biochemistry , gene
The promise of targeted therapies in molecularly defined subsets of cancer has led to a transformation of the process of drug development in oncology. To target cancer successfully and precisely requires high-quality translational data. Such data can be generated by the use of biomarkers that answer key questions in drug development.
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