Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Candidate Reference Method for Total Testosterone in Human Serum | Zendy

Julianne Cook Botelho | Zendy; Christopher Shacklady | Zendy; Hans C. Cooper | Zendy; Susan S.-C. Tai | Zendy; Katleen Van Uytfanghe | Zendy; Linda M. Thienpont | Zendy; Hubert W. Vesper | Zendy

Open Access

Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Candidate Reference Method for Total Testosterone in Human Serum

Author(s) -

Julianne Cook Botelho,

Christopher Shacklady,

Hans C. Cooper,

Susan S.-C. Tai,

Katleen Van Uytfanghe,

Linda M. Thienpont,

Hubert W. Vesper

Publication year - 2012

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2012.190934

Subject(s) - isotope dilution , chromatography , chemistry , testosterone (patch) , mass spectrometry , tandem mass spectrometry , liquid chromatography–mass spectrometry , certified reference materials , detection limit , medicine

We developed and evaluated a candidate reference measurement procedure (RMP) to standardize testosterone measurements, provide highly accurate and precise value assignments for the CDC Hormone Standardization Program, and ensure accurate and comparable results across testing systems and laboratories.

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