Direct Characterization of Motion-Dependent Parameters of Sperm in a Microfluidic Device: Proof of Principle | Zendy

Yuan Chen | Zendy; Ken-Chao Chen | Zendy; Vincent F.S. Tsai | Zendy; Ziwei Huang | Zendy; JuTon Hsieh | Zendy; Andrew M. Wo | Zendy

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Direct Characterization of Motion-Dependent Parameters of Sperm in a Microfluidic Device: Proof of Principle

Author(s) -

Yuan Chen,

Ken-Chao Chen,

Vincent F.S. Tsai,

Ziwei Huang,

JuTon Hsieh,

Andrew M. Wo

Publication year - 2013

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2012.190686

Subject(s) - sperm , beat (acoustics) , microfluidics , materials science , sperm motility , biomedical engineering , biological system , biology , optics , physics , nanotechnology , medicine , botany

Semen analysis is essential for evaluating male infertility. Besides sperm concentration, other properties, such as motility and morphology, are critical indicators in assessing sperm quality. Nevertheless, rapid and complete assessment of these measures still presents considerable difficulty and involves a range of complex issues. Here we present a microfluidic device capable of quantifying a range of properties of human sperm via the resistive pulse technique (RPT).

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