ELISA System for Human Endothelial Lipase
Author(s) -
Tatsuro Ishida,
Kazuya Miyashita,
Mamoru Shimizu,
Noriaki Kinoshita,
Kenta Mori,
Li Sun,
Tomoyuki Yasuda,
Shigeyuki Imamura,
Katsuyuki Nakajima,
Kimber L. Stanhope,
Peter J. Havel,
Ken–ichi Hirata
Publication year - 2012
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.187914
Subject(s) - recombinant dna , chinese hamster ovary cell , hepatic lipase , immunoassay , antibody , chemistry , endocrinology , triglyceride , monoclonal antibody , lipoprotein lipase , lipoprotein , cholesterol , titer , medicine , lipase , microbiology and biotechnology , biology , enzyme , biochemistry , immunology , receptor , gene
Endothelial lipase (EL) regulates the metabolism of HDL cholesterol (HDL-C). However, the role of EL in regulating plasma HDL-C concentrations and EL's potential involvement in atherosclerosis in humans has not been fully investigated due to the lack of reliable assays for EL mass. We developed an ELISA system for serum EL mass.
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