The Early Detection Research Network's Specimen Reference Sets: Paving the Way for Rapid Evaluation of Potential Biomarkers | Zendy

Ziding Feng | Zendy; Jacob Kagan | Zendy; Margaret S. Pepe | Zendy; Mark Thornquist | Zendy; Jo Ann Rinaudo | Zendy; Jackie Dahlgren | Zendy; Karl E. Krueger | Zendy; Yingye Zheng | Zendy; Christos Patriotis | Zendy; Ying Huang | Zendy; Lynn Sorbara | Zendy; Ian M. Thompson | Zendy; Sudhir Srivastava | Zendy

Open Access

The Early Detection Research Network's Specimen Reference Sets: Paving the Way for Rapid Evaluation of Potential Biomarkers

Author(s) -

Ziding Feng,

Jacob Kagan,

Margaret S. Pepe,

Mark Thornquist,

Jo Ann Rinaudo,

Jackie Dahlgren,

Karl E. Krueger,

Yingye Zheng,

Christos Patriotis,

Ying Huang,

Lynn Sorbara,

Ian M. Thompson,

Sudhir Srivastava

Publication year - 2012

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2012.185140

Subject(s) - biomarker , computer science , triage , scale (ratio) , resource (disambiguation) , set (abstract data type) , biomarker discovery , process (computing) , medical physics , data mining , data science , medicine , proteomics , emergency medicine , computer network , biochemistry , chemistry , physics , quantum mechanics , gene , programming language , operating system

The mission of the National Cancer Institute's Early Detection Research Network (EDRN) is to identify and validate cancer biomarkers for clinical use. Since its inception, EDRN investigators have learned a great deal about the process of validating biomarkers for clinical use. Translational research requires a broad spectrum of research expertise, and coordinating collaborative activities can be challenging. The EDRN has developed a robust triage and validation system that serves the roles of both "facilitator" and "brake."

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