Open AccessWhole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based Assay
Author(s) -
Marisa Ninivaggi,
Rafael ApitzCastro,
Yesim Dargaud,
Bas de Laat,
H.C. Hemker,
Theo Lindhout
Publication year - 2012
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2012.184077
Subject(s) - whole blood , thrombin , thrombin generation , tissue factor , platelet poor plasma , chemistry , platelet , blood cell , coagulation , immunology , medicine
The calibrated automated thrombogram (CAT) assay in plasma is a versatile tool to investigate patients with hypo- or hypercoagulable phenotypes. The objective was to make this method applicable for whole blood measurements.
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