Diagnostic Accuracy of Point-of-Care Fecal Calprotectin and Immunochemical Occult Blood Tests for Diagnosis of Organic Bowel Disease in Primary Care: The Cost-Effectiveness of a Decision Rule for Abdominal Complaints in Primary Care (CEDAR) Study
Author(s) -
Liselotte Kok,
Sjoerd G. Elias,
Ben J.�M. Witteman,
Jelle G. Goedhard,
Jean Muris,
Karel G.M. Moons,
Niek J. de Wit
Publication year - 2012
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2011.177980
Subject(s) - calprotectin , medicine , gastroenterology , fecal occult blood , biomarker , colonoscopy , abdominal pain , feces , inflammatory bowel disease , disease , colorectal cancer , cancer , paleontology , biochemistry , chemistry , biology
Fecal biomarker tests that differentiate between organic bowel disease (OBD) and non-OBD in primary care patients with persistent lower-abdomen complaints could reduce the number of unnecessary referrals for endoscopy. We quantified the accuracy of fecal calprotectin and immunochemical occult blood (iFOBT) point-of-care (POC) tests and a calprotectin ELISA in primary care patients with suspected OBD.
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