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Microtube Device for Selectin-Mediated Capture of Viable Circulating Tumor Cells from Blood
Author(s) -
Alun D. Hughes,
Jeff Mattison,
Laura T. Western,
John D. Powderly,
Bryan T. Greene,
Michael R. King
Publication year - 2012
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2011.176669
Subject(s) - circulating tumor cell , selectin , chemistry , tumor cells , cancer research , medicine , immunology , inflammation , metastasis , cancer
Circulating tumor cells (CTCs) can be used clinically to treat cancer. As a diagnostic tool, the CTC count can be used to follow disease progression, and as a treatment tool, CTCs can be used to rapidly develop personalized therapeutic strategies. To be effectively used, however, CTCs must be isolated at high purity without inflicting cellular damage.

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