Open AccessAptameric Molecular Switch for Cascade Signal Amplification
Author(s) -
Cuiping Ma,
Chunhui Zhao,
Yujie Ge,
Chao Shi
Publication year - 2011
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2011.173195
Subject(s) - cascade , signal (programming language) , chemistry , computer science , chromatography , programming language
High sensitivity of analysis is constantly in demand in biomedical research and clinical diagnosis. In recent years aptamer-based analytical methods have been developed for protein detection. We developed a cascade signal amplification strategy based on molecular switches and aptamers to improve protein detection.
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