Serum MicroRNA Expression Profile as a Biomarker in the Diagnosis and Prognosis of Pancreatic Cancer
Author(s) -
Rui Liu,
Xi Chen,
Yiqi Du,
Weiyan Yao,
Lin Shen,
Cheng Wang,
Zhibin Hu,
Rui Zhuang,
Guang Ning,
ChenYu Zhang,
Yaozong Yuan,
ZhaoShen Li,
Ke Zen,
Yi Ba,
Chen-Yu Zhang
Publication year - 2011
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2011.172767
Subject(s) - biomarker , pancreatic cancer , microrna , medicine , oncology , cancer , diagnostic biomarker , bioinformatics , biology , gene , biochemistry
Detection of pancreatic cancer (PaC), particularly at early stages, remains a great challenge owing to lack of specific biomarkers. We sought to identify a PaC-specific serum microRNA (miRNA) expression profile and test its specificity and sensitivity as a biomarker in the diagnosis and prognosis of PaC.
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