Simultaneous Detection of High-Sensitivity Cardiac Troponin I and Myoglobin by Modified Sandwich Lateral Flow Immunoassay: Proof of Principle | Zendy

JiMin Zhu | Zendy; Nengli Zou | Zendy; Danian Zhu | Zendy; Jin Wang | Zendy; Qinghui Jin | Zendy; Jianlong Zhao | Zendy; Hongju Mao | Zendy

Open Access

Simultaneous Detection of High-Sensitivity Cardiac Troponin I and Myoglobin by Modified Sandwich Lateral Flow Immunoassay: Proof of Principle

Author(s) -

JiMin Zhu,

Nengli Zou,

Danian Zhu,

Jin Wang,

Qinghui Jin,

Jianlong Zhao,

Hongju Mao

Publication year - 2011

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2011.171694

Subject(s) - myoglobin , detection limit , troponin i , chromatography , immunoassay , troponin complex , cardiac marker , chemistry , myocardial infarction , materials science , troponin , medicine , cardiology , antibody , biochemistry , immunology

Although numerous lateral flow immunoassays (LFIAs) have been developed and widely used, inadequate analytical sensitivity and the lack of multiple protein detection applications have limited their clinical utility. We developed a new LFIA device for the simultaneous detection of high-sensitivity cardiac troponin I (hs-cTnI) and myoglobin (Myo).

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