Quantification of Methylated Markers with a Multiplex Methylation-Specific Technology | Zendy

Hongzhi Zou | Zendy; Hatim T. Allawi | Zendy; Xiaoming Cao | Zendy; Mike Domanico | Zendy; Jonathan J. Harrington | Zendy; William R. Taylor | Zendy; Tracy C. Yab | Zendy; David A. Ahlquist | Zendy; Graham P. Lidgard | Zendy

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Quantification of Methylated Markers with a Multiplex Methylation-Specific Technology

Author(s) -

Hongzhi Zou,

Hatim T. Allawi,

Xiaoming Cao,

Mike Domanico,

Jonathan J. Harrington,

William R. Taylor,

Tracy C. Yab,

David A. Ahlquist,

Graham P. Lidgard

Publication year - 2011

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2011.171264

Subject(s) - multiplex , microbiology and biotechnology , methylation , gene , dna methylation , biology , multiplex polymerase chain reaction , real time polymerase chain reaction , polymerase chain reaction , gene expression , genetics

Aberrantly methylated genes represent important markers for cancer diagnosis. We describe a multiplex detection approach to efficiently quantify these markers for clinical applications such as colorectal cancer screening.

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