Association of Cognitive Impairment with Combinations of Vitamin B12–Related Parameters | Zendy

Dorte L. Lildballe | Zendy; Sergey N. Fedosov | Zendy; Paul Sherliker | Zendy; Harold Hin | Zendy; Robert Clarke | Zendy; Ebba Nexø | Zendy

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Association of Cognitive Impairment with Combinations of Vitamin B12–Related Parameters

Author(s) -

Dorte L. Lildballe,

Sergey N. Fedosov,

Paul Sherliker,

Harold Hin,

Robert Clarke,

Ebba Nexø

Publication year - 2011

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2011.165944

Subject(s) - methylmalonic acid , homocysteine , vitamin b12 , odds ratio , medicine , cognitive impairment , vitamin , population , b vitamins , gastroenterology , endocrinology , disease , environmental health

Low vitamin B₁₂ concentrations have been associated with higher risks of cognitive impairment, but whether these associations are causal is uncertain. The associations of cognitive impairment with combinations of vitamin B₁₂, holotranscobalamin, methylmalonic acid, and total homocysteine, and with the vitamin B₁₂ transport proteins transcobalamin and haptocorrin, have not been previously studied.

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