Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays | Zendy

Fred S. Apple | Zendy; Paul Collinson | Zendy

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Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays

Author(s) -

Fred S. Apple,

Paul Collinson

Publication year - 2011

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2011.165795

Subject(s) - troponin complex , troponin i , medicine , myocardial infarction , acute coronary syndrome , troponin , clinical practice , roche diagnostics , myocardial infarction diagnosis , analyte , medical laboratory , intensive care medicine , cardiology , pathology , chemistry , chromatography , family medicine

Cardiac troponins I (cTnI) and T (cTnT) have received international endorsement as the standard biomarkers for detection of myocardial injury, for risk stratification in patients suspected of acute coronary syndrome, and for the diagnosis of myocardial infarction. An evidence-based clinical database is growing rapidly for high-sensitivity (hs) troponin assays. Thus, clarifications of the analytical principles for the immunoassays used in clinical practice are important.

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