Rapid Detection of Reassortment of Pandemic H1N1/2009 Influenza Virus
Author(s) -
Leo L. M. Poon,
Polly Mak,
Olive T. W. Li,
Kwok Hung Chan,
Y. M. Cheung,
S. K. Edward,
HuiLing Yen,
Dhanasekaran Vijaykrishna,
Yi Guan,
Malik Peiris
Publication year - 2010
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2010.149179
Subject(s) - reassortment , virology , pandemic , virus , biology , influenza a virus , h5n1 genetic structure , antigenic shift , influenza a virus subtype h5n1 , antigenic drift , covid-19 , infectious disease (medical specialty) , medicine , disease , pathology
Influenza viruses can generate novel reassortants in coinfected cells. The global circulation and occasional introductions of pandemic H1N1/2009 virus in humans and in pigs, respectively, may allow this virus to reassort with other influenza viruses. These possible reassortment events might alter virulence and/or transmissibility of the new reassortants. Investigations to detect such possible reassortants should be included as a part of pandemic influenza surveillance plans.
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