Open AccessMonitoring of Therapy in Congenital Adrenal Hyperplasia
Author(s) -
Andrew Dauber,
Mark D. Kellogg,
Joseph A. Majzoub
Publication year - 2010
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2010.146035
Subject(s) - congenital adrenal hyperplasia , medicine , endocrinology , mineralocorticoid , glucocorticoid , pregnanediol , testosterone (patch) , androstenedione , androgen , hormone
Congenital adrenal hyperplasia is a group of disorders caused by defects in the adrenal steroidogenic pathways. In its most common form, 21-hydroxylase deficiency, patients develop varying degrees of glucocorticoid and mineralocorticoid deficiency as well as androgen excess. Therapy is guided by monitoring clinical parameters as well as adrenal hormone and metabolite concentrations.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom