Atorvastatin Increases 25-Hydroxy Vitamin D Concentrations in Patients with Polycystic Ovary Syndrome | Zendy

Thozhukat Sathyapalan | Zendy; J. Shepherd | Zendy; Charlotte Arnett | Zendy; AnneMarie Coady | Zendy; Eric S. Kilpatrick | Zendy; Stephen L. Atkin | Zendy

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Atorvastatin Increases 25-Hydroxy Vitamin D Concentrations in Patients with Polycystic Ovary Syndrome

Author(s) -

Thozhukat Sathyapalan,

J. Shepherd,

Charlotte Arnett,

AnneMarie Coady,

Eric S. Kilpatrick,

Stephen L. Atkin

Publication year - 2010

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2010.144014

Subject(s) - polycystic ovary , atorvastatin , placebo , metformin , medicine , endocrinology , vitamin d and neurology , insulin resistance , statin , placebo controlled study , gastroenterology , insulin , double blind , alternative medicine , pathology

It has been shown that many women with polycystic ovary syndrome (PCOS) are 25-hydroxyvitamin D (25OHD) insufficient. Both statin treatment and vitamin D supplementation have been shown to improve biochemical hyperandrogenemia, insulin resistance, and markers of inflammation in patients with PCOS, raising the possibility that some of the statin effects are mediated through vitamin D.

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