Alternative Splicing Variant of Kallikrein-Related Peptidase 8 as an Independent Predictor of Unfavorable Prognosis in Lung Cancer
Author(s) -
Chris Planque,
YunHee Choi,
Serge Guyétant,
Nathalie Heuzé-Vourc’h,
Laurent Briollais,
Yves Courty
Publication year - 2010
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2009.138917
Subject(s) - lung cancer , alternative splicing , medicine , kallikrein , messenger rna , immunology , biology , gene , genetics , biochemistry , enzyme
A relatively unexplored area for biomarker identification is alternative splice variants. We undertook this study to evaluate the usefulness of mRNA isoforms encoded by the KLK8 (kallikrein-related peptidase 8) gene as prognostic markers for lung cancer.
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