Monitoring Therapeutic Efficacy by Real-Time Detection of Mycobacterium tuberculosis mRNA in Sputum | Zendy

Nino Mdivani | Zendy; Haijing Li | Zendy; Maka Akhalaia | Zendy; Medea Gegia | Zendy; L. Goginashvili | Zendy; Douglas S. Kernodle | Zendy; George Khechinashvili | Zendy; YiWei Tang | Zendy

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Monitoring Therapeutic Efficacy by Real-Time Detection of Mycobacterium tuberculosis mRNA in Sputum

Author(s) -

Nino Mdivani,

Haijing Li,

Maka Akhalaia,

Medea Gegia,

L. Goginashvili,

Douglas S. Kernodle,

George Khechinashvili,

YiWei Tang

Publication year - 2009

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2009.124396

Subject(s) - sputum , mycobacterium tuberculosis , tuberculosis , medicine , microbiology and biotechnology , real time polymerase chain reaction , mycobacterium , virology , immunology , biology , pathology , gene , genetics

Current laboratory methods for monitoring the response to therapy for tuberculosis (TB) rely on mycobacterial culture. Their clinical usefulness is therefore limited by the slow growth rate of Mycobacterium tuberculosis. Rapid methods to reliably quantify the response to anti-TB drugs are desirable.

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