Utilizing the Molecular Gateway: The Path to Personalized Cancer Management | Zendy

Jonathan B. Overdevest | Zendy; Dan Theodorescu | Zendy; Jae K. Lee | Zendy

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Utilizing the Molecular Gateway: The Path to Personalized Cancer Management

Author(s) -

Jonathan B. Overdevest,

Dan Theodorescu,

Jae K. Lee

Publication year - 2009

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2008.118554

Subject(s) - personalized medicine , pharmacogenomics , precision medicine , genomics , bioinformatics , medicine , cancer , disease , computational biology , cancer medicine , biology , pathology , gene , genome , biochemistry

Personalized medicine is the provision of focused prevention, detection, prognostic, and therapeutic efforts according to an individual's genetic composition. The actualization of personalized medicine will require combining a patient's conventional clinical data with bioinformatics-based molecular-assessment profiles. This synergistic approach offers tangible benefits, such as heightened specificity in the molecular classification of cancer subtypes, improved prognostic accuracy, targeted development of new therapies, novel applications for old therapies, and tailored selection and delivery of chemotherapeutics.

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