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We evaluated the commutability of a proposed reference material (PRM), with a formulation based on dilution of Certified Reference Material 470 (CRM470), for 24 high-sensitivity C-reactive protein (hsCRP) methods. We also investigated whether calibration by use of PRM was effective in harmonizing results.

clinical chemistry

Standardization of High-Sensitivity Immunoassays for Measurement of C-Reactive Protein; II: Two Approaches for Assessing Commutability of a Reference Material