Presence of Donor-Derived DNA and Cells in the Urine of Sex-Mismatched Hematopoietic Stem Cell Transplant Recipients: Implication for the Transrenal Hypothesis | Zendy

Emily C W Hung | Zendy; Tristan K F Shing | Zendy; S Chim | Zendy; Philip Chun Yeung | Zendy; Rebecca W.Y. Chan | Zendy; Ki Wai Chik | Zendy; Vincent Lee | Zendy; Nancy B. Y. Tsui | Zendy; Chi Kong Li | Zendy; Sze Chuen Cesar Wong | Zendy; Rossa W. K. Chiu | Zendy; Y. M. Dennis Lo | Zendy

Open Access

Presence of Donor-Derived DNA and Cells in the Urine of Sex-Mismatched Hematopoietic Stem Cell Transplant Recipients: Implication for the Transrenal Hypothesis

Author(s) -

Emily C W Hung,

Tristan K F Shing,

S Chim,

Philip Chun Yeung,

Rebecca W.Y. Chan,

Ki Wai Chik,

Vincent Lee,

Nancy B. Y. Tsui,

Chi Kong Li,

Sze Chuen Cesar Wong,

Rossa W. K. Chiu,

Y. M. Dennis Lo

Publication year - 2008

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2008.113530

Subject(s) - urine , dna , microbiology and biotechnology , transplantation , buffy coat , biology , chemistry , immunology , medicine , genetics , biochemistry

The term "transrenal DNA" was coined in 2000 to signify that DNA in urine may come from the passage of plasma DNA through the kidney barrier. Although DNA in the urine has the potential to provide a completely noninvasive source of nucleic acids for molecular diagnosis, its existence remains controversial.

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