Open AccessHigh-Sensitivity Chemiluminescence Immunoassays for Detection of Growth Hormone Doping in Sports
Author(s) -
Martin Bidlingmaier,
Jennifer Suhr,
Andrea Ernst,
Zida Wu,
Alexandra Keller,
Christian J. Strasburger,
Andreas Bergmann
Publication year - 2009
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2008.112458
Subject(s) - chemiluminescence , medicine , endocrinology , chemistry , chromatography
Recombinant human growth hormone (rhGH) is abused in sports, but adequate routine doping tests are lacking. Analysis of serum hGH isoform composition has been shown to be effective in detecting rhGH doping. We developed and validated selective immunoassays for isoform analysis with potential utility for screening and confirmation in doping tests.
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