Polymorphisms in Inflammatory Genes and the Risk of Ischemic Stroke and Transient Ischemic Attack: Results of a Multilocus Genotyping Assay | Zendy

Stefan Greisenegger | Zendy; Sonja Zehetmayer | Zendy; Peter Bauer | Zendy; Georg Endler | Zendy; Julia Ferrari | Zendy; Wilfried Lang | Zendy; Michael Janisiw | Zendy; Lori Steiner | Zendy; Suzanne Cheng | Zendy; Wolfgang Lalouschek | Zendy; Christine Mannhalter | Zendy

Open Access

Polymorphisms in Inflammatory Genes and the Risk of Ischemic Stroke and Transient Ischemic Attack: Results of a Multilocus Genotyping Assay

Author(s) -

Stefan Greisenegger,

Sonja Zehetmayer,

Peter Bauer,

Georg Endler,

Julia Ferrari,

Wilfried Lang,

Michael Janisiw,

Lori Steiner,

Suzanne Cheng,

Wolfgang Lalouschek,

Christine Mannhalter

Publication year - 2008

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2008.112151

Subject(s) - single nucleotide polymorphism , medicine , stroke (engine) , genotyping , univariate analysis , odds ratio , snp , genotype , biology , logistic regression , multivariate analysis , genetics , gene , mechanical engineering , engineering

Single-nucleotide polymorphisms (SNPs) in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of these SNP results have not been replicated, however, and metaanalyses of the effects of inflammation-related genes are rare. We investigated 49 SNPs in 34 genes previously reported to be related to inflammation in our study. We tested 459 patients with acute ischemic stroke or transient ischemic attack and 459 controls individually matched by sex and age.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research