Prognostic Value of Chromogranin A at Admission in Critically Ill Patients: A Cohort Study in a Medical Intensive Care Unit
Author(s) -
Dan Zhang,
Thomas Lavaux,
AnneClaire Voegeli,
Thierry Lavigne,
Vincent Castelain,
Nicolás Meyer,
Rémy Sapin,
Dominique Aunis,
MarieHélène MetzBoutigue,
Francis Schneider
Publication year - 2008
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.102442
Subject(s) - medicine , interquartile range , procalcitonin , chromogranin a , intensive care unit , gastroenterology , prospective cohort study , creatinine , univariate analysis , saps ii , logistic regression , intensive care , biomarker , multivariate analysis , apache ii , sepsis , intensive care medicine , biology , immunohistochemistry , biochemistry
Risk assessments of patients should be based on objective variables, such as biological markers that can be measured routinely. The acute response to stress causes the release of catecholamines from the adrenal medulla accompanied by chromogranin A (CGA). To date, no study has evaluated the prognostic value of CGA in critically ill intensive care unit patients.
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