Cell-Free Plasma DNA as a Predictor of Outcome in Severe Sepsis and Septic Shock | Zendy

Katri Saukkonen | Zendy; Päivi Lakkisto | Zendy; Ville Pettilä | Zendy; Marjut Varpula | Zendy; Sari Karlsson | Zendy; Esko Ruokonen | Zendy; Kari Pulkki | Zendy

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Cell-Free Plasma DNA as a Predictor of Outcome in Severe Sepsis and Septic Shock

Author(s) -

Katri Saukkonen,

Päivi Lakkisto,

Ville Pettilä,

Marjut Varpula,

Sari Karlsson,

Esko Ruokonen,

Kari Pulkki

Publication year - 2008

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2007.101030

Subject(s) - septic shock , sepsis , medicine , intensive care unit , organ dysfunction , cell free fetal dna , gastroenterology , shock (circulatory) , biology , genetics , pregnancy , fetus , prenatal diagnosis

Increased concentrations of cell-free DNA have been found in plasma of septic and critically ill patients. We investigated the value of plasma DNA for the prediction of intensive care unit (ICU) and hospital mortality and its association with the degree of organ dysfunction and disease severity in patients with severe sepsis.

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