Two Mass-Spectrometric Techniques for Quantifying Serine Enantiomers and Glycine in Cerebrospinal Fluid: Potential Confounders and Age-Dependent Ranges
Author(s) -
Sabine A. Fuchs,
Monique G.M. de Sainvan der Velden,
Martina M.J. de Barse,
Martin W. Roeleveld,
Margriet W. B. Hendriks,
L. Dorland,
Leo W. J. Klomp,
Ruud Berger,
Tom J. de Koning
Publication year - 2008
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.100412
Subject(s) - serine , glycine , derivatization , chromatography , amino acid , chemistry , cerebrospinal fluid , enantiomer , mass spectrometry , biochemistry , stereochemistry , medicine , enzyme
The recent discovery and specific functions of D-amino acids in humans are bound to lead to the revelation of D-amino acid abnormalities in human disorders. Therefore, high-throughput analysis techniques are warranted to determine D-amino acids in biological fluids in a routine laboratory setting.
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