Microarray-Based In Vitro Test System for the Discrimination of Contact Allergens and Irritants: Identification of Potential Marker Genes | Zendy

Sandra Szameit | Zendy; Klemens Vierlinger | Zendy; Letizia Farmer | Zendy; Helga Tuschl | Zendy; Christa Noehammer | Zendy

Open Access

Microarray-Based In Vitro Test System for the Discrimination of Contact Allergens and Irritants: Identification of Potential Marker Genes

Author(s) -

Sandra Szameit,

Klemens Vierlinger,

Letizia Farmer,

Helga Tuschl,

Christa Noehammer

Publication year - 2008

Publication title -

clinical chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.705

H-Index - 218

eISSN - 1530-8561

pISSN - 0009-9147

DOI - 10.1373/clinchem.2007.097386

Subject(s) - allergic contact dermatitis , gene , microarray , allergen , immune system , in vitro , microarray analysis techniques , biology , gene expression , immunology , allergy , genetics

Animal tests have been used to characterize the potential of chemicals to produce allergic contact dermatitis, but this approach is increasingly a matter of public and political concern. Our aim was to develop and validate an alternative in vitro test that can identify contact allergens.

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