Development of a Multiplexed Urine Assay for Prostate Cancer Diagnosis
Author(s) -
Tatiana Vener,
Carlo Derecho,
Jonathan Baden,
Haiying Wang,
Yashoda Rajpurohit,
Joanne Skelton,
Jyoti Mehrotra,
Shobha Varde,
Dondapati Chowdary,
Walt Stallings,
Bradley C. Leibovich,
H Robin,
Alexandré Pelzer,
Georg Schäfer,
Marco Auprich,
Sebastian Mannweiler,
Peter Amersdorfer,
Abhijit Mazumder
Publication year - 2008
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.094912
Subject(s) - rectal examination , prostate cancer , medicine , methylation , urine , prostate , prostatectomy , gstp1 , cohort , cancer , urology , dna methylation , prostate biopsy , concordance , oncology , urinary system , gastroenterology , biology , genotype , biochemistry , gene expression , gene
Several studies have demonstrated the value of DNA methylation in urine-based assays for prostate cancer diagnosis. However, a multicenter validation with a clinical prototype has not been published.
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