Electric Field–Enhanced Sensitivity of Grafted Ligands and Receptors
Author(s) -
Ajay Singh Negi,
A. K. Sood
Publication year - 2007
Publication title -
clinical chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.705
H-Index - 218
eISSN - 1530-8561
pISSN - 0009-9147
DOI - 10.1373/clinchem.2007.094417
Subject(s) - receptor , sensitivity (control systems) , field (mathematics) , chemistry , electric field , biophysics , biochemistry , biology , engineering , mathematics , physics , electronic engineering , quantum mechanics , pure mathematics
Particle-based agglutination tests consisting of receptors grafted to colloidal microparticles are useful for detecting small quantities of corresponding ligands of interest in fluid test samples, but detection limits of such tests are limited to a certain concentration and it is most desirable to lower the detection limits and to enhance the rate of recognition of ligands.
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